“Gu Shi Bai Mei” is the series of books which was published by Cuiqing Tang of Ming Dynasty, one of the famous bookstores at that time. This paper, through a systematic sorting and examination, analyzes the characteristics of its compilation via comparing the differences between “Gu Shi Bai Mei” and the traditional reference books with allusions. At the same time, according to the characteristics of different editions of the “Gu Shi Bai Mei” series,the paper further studies on the editions in terms of reasons for the completion of “Ju Jin Gu Shi Bai Mei”, and the unique ways of document selection of “Gu Shi Bai Mei” with different dynasty versions and “Gu Shi Huang Mei”,then it also points out its influence on the subsequent books printed in Cui Qing Tang.