Application of “double low” contrast media injection scheme in coronary CT angiography examination

MO Xukai, LUO Chunliu, LIANG Jianye, WEN Zhiqin, HUANG Jiaxi, SHI Changzheng

Journal of Jinan University Natural Science & Medicine Edition ›› 2019, Vol. 40 ›› Issue (5) : 444-450.

PDF(726 KB)
Fig/Tab
Advanced Search
更多内容请点击
PDF(726 KB)
Journal of Jinan University Natural Science & Medicine Edition ›› 2019, Vol. 40 ›› Issue (5) : 444-450. DOI: 10.11778/j.jdxb.2019.05.010

Application of “double low” contrast media injection scheme in coronary CT angiography examination

  • MO Xukai, LUO Chunliu, LIANG Jianye, WEN Zhiqin, HUANG Jiaxi, SHI Changzheng
Author information +
History +

Abstract

Objective: To investigate the feasibility of low injection volume and low concentration iodine contrast (“double low”) media injection mode in 320-slice spiral CT coronary angiography. Methods: 150 patients (83 males and 67 females) who underwent 320-slice spiral CT coronary angiography were randomly divided into three groups, 50 patients in each group. Group A used two-stage injection mode of 50 mL iopamidol injection whose mass concentration of iodine is 370 mg/mL, group B used three-stage injection mode of 39 mL iopamidol injection, and group C used three-stage injection mode of 39 mL iodixanol injection whose mass concentration of iodine is 320 mg/mL. The CT values, signal to noise ratio, and contrast to noise ratio of main blood vessels were measured and compared. All obtained images were diagnosed by two senior radiologists. Results: There were no significant differences in age, BMI, body weight, heart rate, CT value of superior vena cava, noise value of aortic root, SNR, CNRRCA1 and CNRLM among the three groups (P>0.05). CT values of right atrium, right ventricle, aortic root, pulmonary artery, RCA1, LM and ventricular wall showed statistical significance among the three groups (P<0.05), and the value in group A was higher than that in group B and C. A total of 1822 coronary artery segments were evaluated in the three groups. The image quality scores of coronary artery segments were (1.22±0.53), (1.21±0.51), and (1.27±0.64), respectively. There was no significant difference among the three groups ( 2=0.782, P=0.676). Conclusion: It is feasible to perform coronary angiography in 320-slice spiral CT with low injection volume and low concentration of iodine (320 mg/mL) contrast media.

Key words

320-slice spiral CT / contrast agent / image quality / coronary heart disease

Cite this article

EndNote

Ris (Procite)

Bibtex

Download Citations
MO Xukai, LUO Chunliu, LIANG Jianye, WEN Zhiqin, HUANG Jiaxi, SHI Changzheng. Application of “double low” contrast media injection scheme in coronary CT angiography examination. Journal of Jinan University Natural Science & Medicine Edition. 2019, 40(5): 444-450 https://doi.org/10.11778/j.jdxb.2019.05.010

References

[1] 王怡宁, 吕滨, 曹剑. 冠状动脉CT血管成像扫描与报告书写专家共识[J]. 协和医学杂志, 2019, 10(1): 23-30.
WANG Y N,LÜ B,CAO J.Expert consensus on the scan and report of coronary computed tomography angiography[J]. Medical Journal of Peking Union Medical College Hospital, 2019, 10(1): 23-30.
[2] 莫绪凯, 吴天可, 刘伊勇, 等. 可变螺距技术在320排CT急性胸痛三联检查中的应用[J]. 暨南大学学报(自然科学与医学版), 2018, 39(2): 149-155.
MO X K, WU T K, LIU Y Y, et al.Variable helical pitch(VHP) technique in triple row examination of acute chest pain with 320 row spiral CT[J]. Journal of Jinan University(Natural Science & Medicine Edition), 2018, 39(2): 149-155.
[3] 邓琦, 罗泽斌, 夏俊. 低辐射、低对比剂CT血管成像技术的临床应用现状[J]. 实用放射学杂志, 2014, 30(5): 872-874,892.
DENG Q, LUO Z B, XIA J.Low radiation and low contrast agent in clinical application of CT angiography[J]. Journal of Practical Radiology, 2014, 30(5): 872-874.
[4] 李剑, 石明国, 印弘, 等. 冠状动脉CT成像中依据心率调节对比剂用量的可行性[J]. 中华放射学杂志, 2016,50(11):870-873.
LI J, SHI M G, YIN H, et al.The feasibility of reduced dose of contrast agent dependent on patients' heart rate in coronary CT angiography[J]. Chinese Journal of Radiology, 2016, 50(11): 870-873.
[5] 陈晓侠, 贺太平, 于勇, 等. 个体化最佳单能量图像在能谱双低冠状动脉成像中的应用[J]. 中国医学影像学杂志, 2017, 25(1): 30-33.
CHEN X X, HE T P, YU Y, et al.Application of individualized optimal monochromatic energy images in low radiation dose and contrast dose spectral coronary CT angiography[J]. Chinese Journal of Medical Imaging, 2017, 25(1): 30-33.
[6] MCDONALD R J, MCDONALD J S, BIDA J P, et al.Intravenous contrast material-induced nephropathy: causal or coincident phenomenon?[J]. Radiology, 2016, 278(1): 306.
[7] 杨仁杰, 查云飞, 杨文兵, 等. 基于运动校正算法的自然心率冠状动脉CTA的可行性研究[J]. 临床放射学杂志, 2016, 35(8): 1262-1266.
YANG R J, ZHA Y F, YANG W B, et al.Feasibility of coronary CT angiography based on motion correction algorithm with natural heart rate[J]. Journal of Clinical Radiology, 2016, 35(8): 1262-1266.
[8] TOMIZAWA N, YAMAMOTO K, AKAHANE M, et al.The feasibility of halfcycle reconstruction in high heart rates in coronary CT angiography using 320-row CT[J]. The International Journal of Cardiovascular Imaging, 2013, 29(4): 907-911.
[9] KANG E J, LEE J, LEE K N, et al.An initial randomised study assessing free-breathing CCTA using 320-detector CT[J]. European Radiology, 2013, 23(5): 1199-1209.
[10] 韩磊, 尹卫华, 吕滨, 等. 低管电压、低碘浓度对比剂及迭代重建在冠状动脉CT血管成像中的应用[J]. 中华心血管病杂志, 2015,43(3):234-238.
HAN L, YIN W H, LU B, et al.Application feasibility of low tube voltage and lower iodine concentration contrast medium as well as iterative reconstruction in coronary computed tomography angiography[J]. Chinese Journal of Cardiology, 2015, 43(3): 234-238.
[11] 温志琴, 莫绪凯, 史长征. 低对比剂注射方案在320排CT冠状动脉成像中的研究[J]. CT理论与应用研究, 2018, 27(6): 693-699.
WEN Z Q, MO X K, SHI C Z.Study on low contrast agent injection adopted in 320-slice CT coronary angiography[J]. Computerized Tomography Theory and Applications, 2018, 27(6): 693-699.
[12] 顾圣佳, 秦乐, 马泽鹏, 等. 冠状动脉CTA对比剂注射方案优化的前瞻性研究[J]. 中国医学计算机成像杂志, 2018, 24(1): 32-37.
GU S J, QIN L, MA Z P, et al.A prospective study of optimized contrast media injection protocol for coronary computed tomography angiography[J]. Chinese Computed Medical Imaging, 2018, 24(1): 32-37.
[13] HEIN P A, MAY J, ROGALLA P, et al.Feasibility of contrast material volume reduction in coronary artery imaging using 320-slice volume CT[J]. European Radiology, 2010, 20(6): 1337-1343.
[14] 杨琴, 何其舟, 余飞, 等. 基于体表面积和体重的个体化对比剂方案在冠脉CT血管造影中的应用价值[J]. 解放军医学杂志, 2018, 43(2): 135-139.
YANG Q, HE Q Z, YU F, et al.The value of individualized contrast agent injection regimen in coronary CTA imaging based on body surface area and body weight[J]. Medical Journal of Chinese People's Liberation Army, 2018, 43(2): 135-139.
[15] 杨文才, 骆春柳, 冼朝晖, 等. 320排冠脉CT成像中根据体重调整的对比剂最低用量的可行性研究[J]. 影像诊断与介入放射学, 2014, 23(1): 16-21.
YANG W C, LUO C L, XIAN Z H, et al.Lowest volume of contrast agent for 320-detector row coronary CT angiography[J]. Diagnostic Imaging & Interventional Radiology, 2014, 23(1): 16-21.
[16] 李莉明, 刘杰, 高剑波. 冠状动脉CT成像的个体化低对比剂剂量优化研究[J]. 临床放射学杂志, 2016, 35(12): 1899-1903.
LI L M, LIU J, GAO J B.Coronary CT angiography with optimizing contrast medium based of body mass in CT[J]. Journal of Clinical Radiology, 2016, 35(12): 1899-1903.
[17] 祝小莲, 李文欢, 王慧霞, 等. 双源CT冠状动脉成像: 320mgI/ml替代370mgI/ml对比剂的可行性[J]. 中国医学影像学杂志, 2016, 24(3): 187-190.
ZHU X L, LI W H, WANG H X, et al.Coronary angiography with dual-source CT: A feasibility study to replace 370 mgI/ml with 320 mgI/ml contrast medium[J]. Chinese Journal of Medical Imaging, 2016, 24(3): 187-190.
PDF(726 KB)

249

Accesses

0

Citation

Detail
Sections
Recommended
Contact us
Address: Jinan University No.601 Huangpu Dadao West,Guangzhou,China
Postal Code: 510632
Associate Editors-in-Chief Phone: 020-85227136
Editing Room Phone: 020-85227865
Visited
Total visitors:
Visitors of today:
Now online:
Copyright © Journal of Jinan University Natural Science & Medicine Edition, All Rights Reserved. 粤ICP备12087612号　

/

〈 〉