Figure 3 The influence of inhibition of BDNF-TrkB pathway in the early apoptosis of microvascular endothelial cells under glucose starvation A: The flow cytometry scatter plots of apoptosis of K252a (blocker of BDNF pathway) treated bEnd.3 cells under 48-hour glucose starvation; B: Quantitative analysis of A results. 1)P<0.01.
Figure 4 The influence of inhibition of BDNF expression in apoptosis of microvascular endothelial cells under glucose starvation A: The influence of siBDNF-teated in the expression of BDNF mRNA in bEnd.3 cells; B: The influence of siBDNF-teated in the expression of BDNF mRNA in bEnd.3 cells under 6-hour glucose starvation; C: The flow cytometry scatter plots of apoptosis of siBDNF-treated bEnd.3 cells under 24-hour glucose starvation; D: Quantitative analysis of C results. 1)P<0.05; 2)P<0.01; 3)P<0.001; 4)P<0.0001.
Figure 5 The influence of BDNF in the expression level of PFKM gene A: The influence of siBDNF treatment in the expression of HK2 gene mRNA (a key regulation gene of glycolysis) in bEnd.3 cells under non-glucose starvation and glucose starvation; B: The influence of siBDNF treatment in the expression of PFKM gene mRNA (a key regulation gene of glycolysis) in bEnd.3 cells under non-glucose starvation and glucose starvation. 1)P<0.05; 2)P<0.01; 3)P<0.001.