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Figure/Table detail
Effects and mechanism of Hanjingtang on phenotype conversion and inflammation and oxidative stress in cold coagulation hypertensive rats
LIU Yang, CHEN Guihai
Journal of Jinan University Natural Science & Medicine Edition
, 2023, 44(
4
): 347-357. DOI:
10.11778/j.jdxb.20230010
Figure 2
HE staining results of rat aorta (×200)
Other figure/table from this article
Figure 1
Changes in blood pressure of rats in each group
A: Change in systolic blood pressure in each group of rats($\bar{x}±s$,
n
=9); B: Change in diastolic blood pressure in rats of each group($\bar{x}±s$,
n
=9). 1)Compared with CON group,
P
<0.05; 2)Compared with CON group,
P
<0.01;3)Compared with model group,
P
<0.01.
Figure 3
Masson staining results and collagen fiber expression levels in rat aorta
A:Masson staining results of rat aorta in each group(×200); B:Collagen fiber levels of rat aorta in each group.1)Compared with CON group,
P
<0.01;2)Compared with MOD group,
P
<0.01.
Figure 4
Comparison of the protein levels of α-SMA,OPN,and calponin in the rat aorta
A:Immunohistochemistry assay result of α-SMA in rat aorta of each group(×200);B:Immunohistochemistry assay result of OPN in rat aorta of each group (×200);C:Immunohistochemistry assay result of calponin in rat aorta of each group (×200);D:Expression of α-SMA, OPN and calponin protein levels in rat aorta of each group.1)Compared with CON group,
P
<0.01;2)Compared with MOD group,
P
<0.05;3)Compared with MOD group,
P
<0.01.
Figure 5
Expression levels of SOD and MDA in rat serum of each group
A:Expression level of serum SOD in each group of rats; B:Expression level of serum MDA in each group of rats.1)Compared with CON group,
P
<0.01;2)Compared with MOD group,
P
<0.01.
Figure 6
Expression levels of IL-1β, TNF-α, and NLRP 3 in rat serum of each group
A:Expression level of serum IL-1β in each group of rats;B:Expression level of serum TNF-α in each group of rats; C:Expression level of serum NLRP3 in each group of rats.1)Compared with CON group,
P
<0.01;2)Compared with MOD groups,
P
<0.05; 3)Compared with MOD groups,
P
<0.01.
Figure 7
Expression of Nrf2, NQO1, NF-κB and IκBα proteins in rat aortic tissues of each group analyzed by Western blot
A: Band diagram of protein expression in rat aorta of each group;B: Relative protein expression in rat aorta of each group.1)Compared with CON group,
P
<0.01;2)Compared with MOD group,
P
<0.05;3)Compared with MOD group,
P
<0.01.
Figure 8
The expression of NQO1 and NF-κB genes in the rat aortic tissues was analyzed by Rt-PCR
1)Compared with CON group,
P
<0.01; Compared with MOD group, 2)
P
<0.05, 3)
P
<0.01.
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